Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | CRHBP | P24387 | 3/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21800147 | 0.84 | CRHBP (0.55) | ALDH1A1L3MBTL1CRHBPCRHR2MEN1 | |
| SCHEMBL21800130 | 0.80 | CRHBP (0.51) | ALDH1A1L3MBTL1CRHBPCRHR2MEN1 | |
| SCHEMBL3428051 | 0.75 | MEN1 (0.50) | CYP19A1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21800143 | 0.75 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1ATMLMNASMN1; SMN2 | |
| SCHEMBL1794881 | 0.74 | NPSR1 (0.59) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL21800146 | 0.73 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL1505856 | 0.73 | PKM (0.45) | ALDH1A1L3MBTL1CRHBPCRHR2MEN1 | |
| SCHEMBL7339073 | 0.73 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1CRHBPCRHR2MEN1 | |
| SCHEMBL1792495 | 0.72 | NPSR1 (0.61) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL17592013 | 0.71 | NAPRT (0.53) | ALDH1A1KMT2ALMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640595-B1 | SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 1999-03-24 | — | — | EP | disclosed |
| CN-1039228-C | Novel substituted tert-amino compund | YAMANOUCHI PHARMA CO LTD (JP) | 1998-07-22 | — | — | CN | disclosed |
| US-5538976-A | ANTICARCINOGENIC AGENTS AND ENZYME INHIBITORS FOR AROMATASE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0640595-A1 | NOVEL SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |
| CN-1079962-A | New substituted tertiary amine compound and salt thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1993-12-29 | — | — | CN | disclosed |