Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325956 | 0.88 | PIM1 (0.44) | PRKD3PIM1GSK3AGSK3BIRAK1 | |
| SCHEMBL8318717 | 0.85 | LMNA (0.40) | PRKD3PIM1GSK3AGSK3BIRAK1 | |
| SCHEMBL8324820 | 0.84 | PRKD3 (0.34) | PRKD3PIM1GSK3AGSK3BIRAK1 | |
| SCHEMBL8323758 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1LMNACYP1A2TOP2A | |
| SCHEMBL8323544 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8322831 | 0.77 | ALDH1A1 (0.35) | PRKD3PIM1GSK3AGSK3BIRAK1 | |
| SCHEMBL8323756 | 0.75 | KDM4E (0.58) | KDM4EALDH1A1LMNACYP1A2TOP2A | |
| SCHEMBL8321528 | 0.75 | ALDH1A1 (0.43) | KDM4EALDH1A1LMNACYP1A2TOP2A | |
| SCHEMBL8323542 | 0.75 | DRD3 (0.58) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8323539 | 0.74 | KMT2A (0.33) | PRKD3PIM1GSK3AGSK3BIRAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |