Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326252 | 0.76 | NPC1 (0.48) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL8330984 | 0.76 | KDM4E (0.44) | BRD4KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15057591 | 0.69 | CYP1A2 (0.36) | KDM4ENPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL7219605 | 0.67 | L3MBTL1 (0.49) | BRD4HPGDALDH1A1 | |
| SCHEMBL8332147 | 0.67 | KDM4E (0.44) | BRD4KDM4ENPC1RAB9AGAA | |
| SCHEMBL8331583 | 0.66 | EGFR (0.50) | BRD4KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL8326221 | 0.66 | KDM4E (0.46) | BRD4KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7329963 | 0.66 | ELANE (0.57) | KDM4EALDH1A1 | |
| SCHEMBL8328519 | 0.66 | PTGS2 (0.47) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL4254282 | 0.66 | KDM4E (0.46) | KDM4ENPC1SMN1; SMN2GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994270-A | CONTROLLING GAEUMANNOMYCES | MONSANTO COMPANY (US) | 1999-11-30 | — | — | US | disclosed |
| EP-0619297-B1 | Fungicides for the control of take-all desease of plants | MONSANTO CO (US) | 1997-06-18 | — | — | EP | disclosed |
| EP-0619297-A1 | Fungicides for the control of take-all desease of plants | MONSANTO COMPANY (US) | 1994-10-12 | — | — | EP | disclosed |