Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330984 | 0.77 | KDM4E (0.44) | NPC1RAB9ASMN1; SMN2GAAMAPK1 | |
| SCHEMBL8326263 | 0.76 | BRD4 (0.41) | NPC1RAB9ASMN1; SMN2GAARXFP1 | |
| SCHEMBL30753472 | 0.73 | CYP2C19 (0.54) | NPC1RAB9AGAAKDM4EHCRTR1 | |
| SCHEMBL8328519 | 0.70 | PTGS2 (0.47) | NPC1RAB9ASMN1; SMN2GAAHDAC1 | |
| SCHEMBL22846884 | 0.68 | KDM4E (0.41) | NPC1RAB9ASMN1; SMN2GAAKDM4E | |
| SCHEMBL25463759 | 0.68 | MAOB (0.63) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL9130415 | 0.68 | LMNA (0.58) | NPC1RXFP1LMNAKDM4EALDH1A1 | |
| SCHEMBL490183 | 0.68 | TTR (0.63) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6240044 | 0.66 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2GAARXFP1 | |
| SCHEMBL9690609 | 0.66 | GPR55 (0.64) | NPC1RAB9ASMN1; SMN2GAARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994270-A | CONTROLLING GAEUMANNOMYCES | MONSANTO COMPANY (US) | 1999-11-30 | — | — | US | disclosed |
| EP-0619297-B1 | Fungicides for the control of take-all desease of plants | MONSANTO CO (US) | 1997-06-18 | — | — | EP | disclosed |
| EP-0619297-A1 | Fungicides for the control of take-all desease of plants | MONSANTO COMPANY (US) | 1994-10-12 | — | — | EP | disclosed |