Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | MELK | Q14680 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329045 | 0.89 | MAPT (0.53) | POLBMAPTPAX8GAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL8331150 | 0.88 | MAPT (0.52) | POLBMAPTPAX8GAAKDM4E | |
| SCHEMBL8561203 | 0.88 | GAA (0.49) | MAPTPAX8GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL8328843 | 0.85 | MEN1 (0.42) | MEN1KMT2APOLBMAPTUSP2 | |
| SCHEMBL8328001 | 0.82 | MELK (0.47) | MEN1KMT2APOLBMAPTUSP2 | |
| SCHEMBL8329054 | 0.81 | MAPT (0.42) | MEN1KMT2APOLBMAPTUSP2 | |
| SCHEMBL8668728 | 0.78 | MAPT (0.47) | POLBMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8561277 | 0.78 | PDE4B (0.61) | MEN1KMT2AMAPTPAX8GAA | |
| Hydrochloric Acid SCHEMBL8563873 | 0.77 | PDE4B (0.60) | MEN1KMT2AMAPTPAX8GAA | |
| SCHEMBL8323951 | 0.77 | MAPT (0.41) | MEN1KMT2AMAPTPABPC1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705260-B1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AG (DE) | 1999-03-03 | — | — | EP | claimed |