Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327888 | 0.86 | MAPT (0.38) | MAPTKMT2AMEN1POLBADORA1 | |
| SCHEMBL8328444 | 0.83 | MAPT (0.42) | MAPTKMT2AMEN1POLBPIK3CA | |
| SCHEMBL8326516 | 0.81 | MEN1 (0.46) | MAPTKMT2AMEN1POLBPIK3CA | |
| SCHEMBL8329045 | 0.75 | MAPT (0.53) | MAPTPOLBNPSR1 | |
| Hydrochloric Acid SCHEMBL8331150 | 0.74 | MAPT (0.52) | MAPTPOLBKDM4ENPSR1 | |
| SCHEMBL8327174 | 0.71 | P2RX3 (0.43) | — | |
| SCHEMBL8328970 | 0.71 | PDE4B (0.40) | MAPTKMT2AMEN1POLBPIK3CA | |
| SCHEMBL8328001 | 0.70 | MELK (0.47) | MAPTKMT2AMEN1POLBPIK3CA | |
| SCHEMBL8561203 | 0.70 | GAA (0.49) | MAPTNPSR1RAB9A | |
| SCHEMBL8330323 | 0.70 | MAPK8 (0.42) | MAPTADORA1MAPK8RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705260-B1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AG (DE) | 1999-03-03 | — | — | EP | claimed |