Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585800 | 0.78 | CASP1 (0.32) | — | |
| SCHEMBL6585204 | 0.77 | KDM4E (0.31) | ALDH1A1MAPTKDM4ECYP1A2CYP2D6 | |
| SCHEMBL29079914 | 0.75 | EPHX2 (0.36) | ALDH1A1MAPK1MEN1KMT2AATM | |
| SCHEMBL6585692 | 0.75 | MEN1 (0.37) | ALDH1A1ADORA2BMAPK1MEN1KMT2A | |
| SCHEMBL8326659 | 0.74 | KDM4E (0.45) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL29079929 | 0.68 | ALDH1A1 (0.32) | ALDH1A1ADORA2BMAPK1MEN1KMT2A | |
| SCHEMBL29079808 | 0.66 | UCHL1 (0.38) | MAPK1MEN1KMT2AMAPT | |
| SCHEMBL28242066 | 0.65 | GAA (0.37) | ALDH1A1MAPK1MAPTCYP1A2HSD17B10 | |
| SCHEMBL29008584 | 0.64 | EPHX2 (0.34) | MAPK1MEN1KMT2AATMMAPT | |
| SCHEMBL3898727 | 0.64 | ALDH1A1 (0.36) | ALDH1A1MAPK1KDM4ECYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944621-B1 | 2-IMIDAZOLINYLAMINOINDOLE COMPOUNDS USEFUL AS ALPHA-2 ADRENOCEPTOR AGONISTS | PROCTER & GAMBLE (US) | 2004-09-01 | — | — | EP | disclosed |