Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.33 |
| ▸ | MICA | Q29983 | 2/20 | 0.33 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.33 |
| ▸ | POLQ | O75417 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327868 | 0.88 | MAPT (0.38) | MAPTGPBAR1TRPM8POLQ | |
| SCHEMBL9030025 | 0.84 | GPBAR1 (0.38) | MAPTGPBAR1 | |
| SCHEMBL8328842 | 0.81 | NPC1 (0.38) | MAPTNPC1POLBTRPM8GAA | |
| SCHEMBL8328825 | 0.77 | SSTR4 (0.38) | MAPTNPC1POLBTRPM8GAA | |
| SCHEMBL8745964 | 0.75 | ITGB1 (0.41) | POLQ | |
| SCHEMBL8550618 | 0.74 | LIPE (0.43) | GPBAR1POLQ | |
| SCHEMBL8549639 | 0.74 | GPBAR1 (0.37) | MAPTGPBAR1RBP4MGLL | |
| SCHEMBL9029347 | 0.73 | ROCK2 (0.37) | NPC1GPBAR1GAA | |
| SCHEMBL8327409 | 0.70 | NPC1 (0.38) | MAPTNPC1POLBTRPM8GAA | |
| SCHEMBL29435625 | 0.70 | RPS6KA3 (0.39) | NPC1POLBTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758321-B1 | 3-SUBSTITUTED PYRIDINE COMPOUNDS AND DERIVATIVES THEREOF AS HERBICIDES | ZENECA LTD (GB) | 1999-04-21 | — | — | EP | disclosed |
| US-5763357-A | HERBICIDES | ZENECA LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |
| EP-0758321-A1 | 3-SUBSTITUTED PYRIDINE COMPOUNDS AND DERIVATIVES THEREOF AS HERBICIDES | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| US-5595958-A | HERBICIDES | ZENECA LIMITED (GB) | 1997-01-21 | — | — | US | disclosed |
| WO-1995029893-A1 | 3-SUBSTITUTED PYRIDINE COMPOUNDS AND DERIVATIVES THEREOF AS HERBICIDES | ZENECA LIMITED (GB) | 1995-11-09 | — | — | WO | disclosed |