Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356014 | 0.82 | CYP1B1 (0.53) | POLBALDH1A1CYP1A2MAPTMEN1 | |
| SCHEMBL8325336 | 0.74 | XDH (0.48) | MAPTEGFRRETKDRNPSR1 | |
| SCHEMBL7310036 | 0.74 | CYP1B1 (0.55) | POLBALDH1A1CYP1A2MAPTMEN1 | |
| SCHEMBL7303648 | 0.72 | CYP1B1 (0.51) | POLBALDH1A1CYP1A2MAPTMEN1 | |
| SCHEMBL7304881 | 0.68 | CYP1B1 (0.53) | POLBALDH1A1CYP1A2MAPTMEN1 | |
| SCHEMBL7307391 | 0.68 | CYP1B1 (0.53) | POLBALDH1A1CYP1A2MAPTMEN1 | |
| SCHEMBL7310271 | 0.67 | EGFR (0.57) | EGFR | |
| SCHEMBL7306885 | 0.67 | CYP1B1 (0.54) | CYP3A4KDM4EHPGDPOLBCYP2C9 | |
| SCHEMBL7309697 | 0.66 | CYP1B1 (0.58) | POLBALDH1A1CYP1A2MAPTMEN1 | |
| SCHEMBL7317399 | 0.66 | EGFR (0.52) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004047817-A1 | PDE4 AND PDE3/4 INHIBITORS FOR USE IN THE TREATMENT OF CACHEXIA | ALTANA PHARMA AG (DE) | 2004-06-10 | — | — | WO | disclosed |