Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965403 | 0.91 | HCRTR1 (0.34) | ABL1SMOHCRTR1FFAR4PLAU | |
| SCHEMBL7962948 | 0.91 | PLAU (0.35) | ABL1SMOHCRTR1PLAUFPR1 | |
| SCHEMBL7965416 | 0.88 | ABL1 (0.37) | ABL1SMOHCRTR1FPR1FPR2 | |
| SCHEMBL8330824 | 0.85 | DHODH (0.43) | DHODHABL1NAPRTHCRTR1FFAR4 | |
| SCHEMBL8330821 | 0.85 | DHODH (0.36) | DHODHABL1NAPRTFFAR4PLAU | |
| SCHEMBL8327934 | 0.83 | DHODH (0.35) | DHODHABL1NAPRTFFAR4ELANE | |
| SCHEMBL8328159 | 0.83 | DHODH (0.37) | DHODHABL1NAPRTHCRTR1FFAR4 | |
| SCHEMBL7962136 | 0.82 | KCNMA1 (0.35) | ABL1 | |
| SCHEMBL7952972 | 0.80 | HCRTR1 (0.34) | DHODHHCRTR1 | |
| SCHEMBL7961238 | 0.80 | ALDH1A1 (0.32) | HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946555-A1 | PYRROLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 1999-10-06 | — | — | EP | claimed |
| WO-1998025925-A1 | PYRROLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1998-06-18 | — | — | WO | claimed |
| EP-0946555-A1 | PYRROLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998025925-A1 | PYRROLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1998-06-18 | — | — | WO | disclosed |