Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 8/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 2/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963301 | 0.90 | HCRTR1 (0.34) | HCRTR1IDO1SCN9AMEN1KMT2A | |
| SCHEMBL7965403 | 0.89 | HCRTR1 (0.34) | ABL1HCRTR1SCN9AFPR1FPR2 | |
| SCHEMBL8327360 | 0.88 | DHODH (0.35) | ABL1HCRTR1FPR1FPR2SMO | |
| SCHEMBL7967665 | 0.87 | ABL1 (0.35) | ABL1HCRTR1IDO1CDC7DBF4 | |
| SCHEMBL7962948 | 0.87 | PLAU (0.35) | ABL1HCRTR1FPR1FPR2SMO | |
| SCHEMBL7962621 | 0.87 | ABL1 (0.35) | ABL1HCRTR1IDO1SCN9ACDC7 | |
| SCHEMBL7964731 | 0.87 | FPR1 (0.35) | ABL1IDO1FPR1FPR2CDC7 | |
| SCHEMBL7962855 | 0.84 | HCRTR1 (0.37) | ABL1HCRTR1CDC7DBF4MEN1 | |
| SCHEMBL7963509 | 0.82 | CFTR (0.40) | ABL1HCRTR1CYP1A2HTR2AHTR2C | |
| SCHEMBL8328159 | 0.80 | DHODH (0.37) | ABL1HCRTR1IDO1SCN9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | claimed |
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | disclosed |