Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 6/20 | 0.50 |
| ▸ | WNT3A | P56704 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | RBP4 | P02753 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489374 | 0.81 | CES2 (0.55) | LMNA | |
| SCHEMBL8191987 | 0.81 | L3MBTL1 (0.43) | L3MBTL1 | |
| SCHEMBL8488889 | 0.80 | KDM4E (0.44) | CYP2C19L3MBTL1 | |
| SCHEMBL8439499 | 0.78 | LMNA (0.53) | CTNNB1WNT3ALMNAGAA | |
| SCHEMBL31475594 | 0.77 | LMNA (0.56) | CTNNB1WNT3ALMNAGAAPTGS1 | |
| SCHEMBL2494518 | 0.77 | LMNA (0.56) | CTNNB1WNT3ALMNAGAAPTGS1 | |
| SCHEMBL3474396 | 0.77 | LMNA (0.56) | CTNNB1WNT3ALMNAGAAPTGS1 | |
| SCHEMBL8489375 | 0.77 | LMNA (0.56) | CTNNB1WNT3ALMNAGAAPTGS1 | |
| SCHEMBL8328384 | 0.77 | HDAC6 (0.45) | CTNNB1WNT3ALMNACYP2C9RBP4 | |
| SCHEMBL1950901 | 0.76 | CTNNB1 (0.57) | CTNNB1WNT3ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929510-A2 | PROCESSES FOR THE PREPARATION OF ARYL-$g(b)-DIKETONES, ARYL-PYRIMIDINE KETONES AND CROP PROTECTION INTERMEDIATES | ZENECA LIMITED (GB) | 1999-07-21 | — | — | EP | disclosed |
| US-5925795-A | Processes for the preparation of aryl-β-diketones, arylpyrimidine ketones and crop protection intermediates | ZENECA LIMITED (GB) | 1999-07-20 | — | — | US | disclosed |
| EP-0927169-A1 | 4-CYCLOALKYL-5-SUBSTITUTED PYRIMIDINE COMPOUNDS USEFUL AS CROP PROTECTION AGENTS | ZENECA LIMITED (GB) | 1999-07-07 | — | — | EP | disclosed |
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| WO-1998011074-A1 | 4-CYCLOALKYL-5-SUBSTITUTED PYRIMIDINE COMPOUNDS USEFUL AS CROP PROTECTION AGENTS | ZENECA LIMITED (GB) | 1998-03-19 | — | — | WO | disclosed |
| WO-1998011046-A2 | PROCESSES FOR THE PREPARATION OF ARYL-β-DIKETONES, ARYL-PYRIMIDINE KETONES AND CROP PROTECTION INTERMEDIATES | ZENECA LIMITED (GB) | 1998-03-19 | — | — | WO | disclosed |
| US-5707930-A | HERBICIDES, AGRICULTURE | ZENECA LIMITED (GB) | 1998-01-13 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| EP-0418175-B1 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-07-17 | — | — | EP | disclosed |
| EP-0418175-A2 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1991-03-20 | — | — | EP | disclosed |