Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323805 | 0.81 | KMT2A (0.51) | POLBMAOBKDM4EKMT2A | |
| SCHEMBL8330129 | 0.81 | CYP2D6 (0.49) | GAA | |
| Hydrochloric Acid SCHEMBL9211501 | 0.79 | ALDH1A1 (0.49) | ALDH1A1POLBGAAMAOAMAOB | |
| SCHEMBL8323528 | 0.79 | ALDH1A1 (0.59) | ALDH1A1POLBGAAMAOAMAOB | |
| SCHEMBL8326524 | 0.79 | ALDH1A1 (0.59) | ALDH1A1POLBGAAMAOAMAOB | |
| SCHEMBL8329181 | 0.79 | MAPT (0.67) | ALDH1A1POLBGAAMAOAMAOB | |
| SCHEMBL4854039 | 0.77 | NR1H3 (0.62) | ALDH1A1LMNAUTS2RKMT2A | |
| SCHEMBL9208530 | 0.74 | BCHE (0.50) | MAOBKDM4E | |
| SCHEMBL21926319 | 0.72 | LMNA (0.69) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL1474833 | 0.72 | UTS2R (0.74) | ALDH1A1LMNAUTS2RKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |