Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 2/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18656052 | 0.71 | LPO (0.32) | — | |
| SCHEMBL8328828 | 0.63 | AOC3 (0.45) | GRIA2GRIA4EGFRSRC | |
| SCHEMBL19486386 | 0.62 | — | — | |
| SCHEMBL7922166 | 0.56 | LMNA (0.41) | GRIA2GRIA4 | |
| SCHEMBL16402408 | 0.56 | GAA (0.39) | GRIA2GRIA4 | |
| SCHEMBL11320669 | 0.54 | LPO (0.44) | — | |
| SCHEMBL12507811 | 0.52 | ALDH1A1 (0.36) | EGFRSRC | |
| SCHEMBL9564333 | 0.50 | DYRK1A (0.44) | GRIA4EGFRSRC | |
| SCHEMBL13390161 | 0.49 | MEN1 (0.52) | — | |
| SCHEMBL12147468 | 0.49 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |