Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321742 | 0.92 | PKM (0.37) | GSK3BDRD4SIGMAR1TMEM97MEN1 | |
| SCHEMBL8328809 | 0.91 | POLB (0.38) | POLBDRD4SIGMAR1TMEM97PDE2A | |
| SCHEMBL8327681 | 0.89 | DRD4 (0.41) | GSK3BPOLBDRD4SIGMAR1PDE2A | |
| SCHEMBL8330567 | 0.89 | POLB (0.38) | GSK3BPOLBDRD4SIGMAR1TMEM97 | |
| SCHEMBL8328371 | 0.89 | NOS3 (0.35) | — | |
| SCHEMBL8326763 | 0.83 | DRD4 (0.41) | DRD4 | |
| SCHEMBL8326577 | 0.81 | ALDH1A1 (0.34) | SIGMAR1 | |
| SCHEMBL8328418 | 0.79 | POLB (0.44) | KAT2BPOLBMAOBMEN1KMT2A | |
| SCHEMBL8328988 | 0.76 | KDM4E (0.31) | DRD4MAOBMEN1KMT2A | |
| SCHEMBL8327693 | 0.76 | DRD4 (0.41) | DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |