Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328415 | 0.89 | GSK3B (0.36) | — | |
| SCHEMBL8326763 | 0.82 | DRD4 (0.41) | — | |
| SCHEMBL8326577 | 0.82 | ALDH1A1 (0.34) | — | |
| SCHEMBL8321742 | 0.80 | PKM (0.37) | NOS3NOS1NOS2 | |
| SCHEMBL8328809 | 0.80 | POLB (0.38) | — | |
| SCHEMBL8328988 | 0.79 | KDM4E (0.31) | — | |
| SCHEMBL8327173 | 0.79 | PRKAA2 (0.42) | — | |
| SCHEMBL8328374 | 0.78 | ACHE (0.42) | — | |
| SCHEMBL8327681 | 0.78 | DRD4 (0.41) | — | |
| SCHEMBL8330567 | 0.77 | POLB (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |