Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326151 | 0.80 | CYP1A2 (0.41) | CCNA2CDK2KDM4EALDH1A1POLB | |
| SCHEMBL8329431 | 0.76 | CCNA2 (0.44) | CCNA2CDK2CA2CA4CA9 | |
| SCHEMBL8327878 | 0.74 | CCNA2 (0.34) | CCNA2CDK2CA2CA4CA9 | |
| SCHEMBL8327052 | 0.74 | CDK2 (0.35) | CCNA2CDK2CA2CA4CA9 | |
| SCHEMBL8325671 | 0.72 | CCNA2 (0.40) | CCNA2CDK2KDM4E | |
| SCHEMBL8326389 | 0.71 | CCNT1 (0.39) | CDK2EGFRKDM4EALDH1A1 | |
| SCHEMBL8327012 | 0.67 | CYP2A6 (0.46) | CCNA2CDK2KDM4EALDH1A1POLB | |
| SCHEMBL8327283 | 0.67 | CYP2C19 (0.42) | CCNA2CDK2EGFRKDM4EALDH1A1 | |
| SCHEMBL8330196 | 0.65 | CCNA2 (0.43) | CCNA2CDK2CA2CA4CA9 | |
| SCHEMBL8327915 | 0.64 | CYP2A6 (0.45) | KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915879-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998001449-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-01-15 | — | — | WO | disclosed |