Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322773 | 0.92 | CHRM1 (0.46) | CHRM1 | |
| SCHEMBL8325881 | 0.91 | CHRM1 (0.45) | CHRM1 | |
| SCHEMBL8329298 | 0.87 | AGTR1 (0.46) | — | |
| SCHEMBL8328347 | 0.83 | CHRM1 (0.41) | CHRM1LMNASERPINE1 | |
| SCHEMBL4729358 | 0.81 | ABCB11 (0.47) | — | |
| SCHEMBL8323834 | 0.81 | CHRM1 (0.40) | CHRM1SERPINE1 | |
| SCHEMBL9044702 | 0.80 | AGTR1 (0.46) | — | |
| SCHEMBL8325882 | 0.80 | CHRM1 (0.39) | CHRM1SERPINE1 | |
| SCHEMBL9049056 | 0.80 | AGTR1 (0.45) | — | |
| SCHEMBL4935797 | 0.79 | AGTR1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498721-B1 | N-substituted quinoline derivatives, process for their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (FR) | 1999-12-22 | — | — | EP | claimed |