Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | GLO1 | Q04760 | 5/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
| ▸ | CHUK | O15111 | 1/20 | 0.51 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | SNCA | P37840 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | APP | P05067 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2216850 | 0.94 | MAPT (0.66) | MAPTGLO1ABL1IKBKBCHUK | |
| SCHEMBL2903282 | 0.86 | KMT2A (0.60) | MAPTALDH1A1KMT2AMEN1EGFR | |
| SCHEMBL29799957 | 0.83 | MAPT (0.70) | MAPTGLO1ABL1IKBKBCHUK | |
| SCHEMBL934307 | 0.83 | MAPT (0.70) | MAPTGLO1ABL1IKBKBCHUK | |
| SCHEMBL2215798 | 0.81 | MAPT (0.69) | MAPTGLO1ABL1IKBKBCHUK | |
| SCHEMBL168150 | 0.80 | MAPT (0.67) | MAPTGLO1ABL1IKBKBCHUK | |
| SCHEMBL29601206 | 0.80 | MAPT (0.67) | MAPTGLO1ABL1IKBKBCHUK | |
| SCHEMBL8328530 | 0.80 | LMNA (0.63) | MAPTALDH1A1KMT2AMEN1CYP2C9 | |
| Vanillin SCHEMBL6468390 | 0.80 | ALDH1A1 (0.62) | MAPTGLO1ALDH1A1KMT2AMEN1 | |
| SCHEMBL2211610 | 0.80 | KDM4E (0.56) | MAPTALDH1A1KMT2AMEN1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006566-A2 | MONOMETHOXY-HYDROXY-BENZYLMALONATES | MERCK PATENT GMBH (DE) | 2011-01-20 | — | — | WO | disclosed |