Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 19/20 | 0.48 |
| ▸ | RARA | P10276 | 18/20 | 0.48 |
| ▸ | RARG | P13631 | 18/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240904 | 0.81 | RARB (0.71) | RARBRARARARG | |
| SCHEMBL6234600 | 0.81 | RARA (0.53) | RARBRARARARG | |
| SCHEMBL8328655 | 0.80 | RARB (0.52) | RARBRARARARGNPC1RAB9A | |
| SCHEMBL6397552 | 0.74 | RARB (0.51) | RARBRARARARG | |
| SCHEMBL8335174 | 0.72 | RARB (0.42) | RARBRARARARGNPC1RAB9A | |
| SCHEMBL8329424 | 0.72 | RARA (0.42) | RARBRARARARG | |
| SCHEMBL8580707 | 0.71 | RARB (0.61) | RARBRARARARG | |
| SCHEMBL8771689 | 0.69 | PDK2 (0.49) | RARBRARARARGRAB9A | |
| SCHEMBL17275573 | 0.69 | RARB (0.50) | RARBRARARARG | |
| SCHEMBL8771880 | 0.67 | RARA (0.55) | RARBRARARARGNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958954-A | 2,2-DIALKYL-4-ARYL-SUBSTITUTED BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES | ALLERGAN SALES, INC. (US) | 1999-09-28 | — | — | US | disclosed |
| US-5952345-A | RETINOID ACID RECEPTOR ANTAGONIST; A DERIVATIVES OF ARYL-SUBSTITUTED AND ARYL (3-OXO-1-PROPENLY)-SUBSTITUTED BENZOPYRAN, BENZOTHIOPYRAN, 1,2-DIHYDROQUINOLINE; PREVENTING TOXICITY OR SIDE EFFECTS CAUSED BY RETINOIDS OR VITAMIN A | ALLERGAN SALES, INC. (US) | 1999-09-14 | — | — | US | disclosed |
| US-5877207-A | SKIN DISORDERS; ANTICARCINOGENIC AGENTS | ALLERGAN SALES, INC. (US) | 1999-03-02 | — | — | US | disclosed |