Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 4/20 | 0.33 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8332231 | 0.80 | KDM4E (0.36) | CNR2CNR1KDM4ERECQLDPP4 | |
| SCHEMBL7961452 | 0.79 | KCNMA1 (0.38) | KDM4ERECQLDPP4PDE4AKCNMA1 | |
| SCHEMBL7963738 | 0.78 | KCNMA1 (0.37) | DPP4KCNMA1 | |
| SCHEMBL7967718 | 0.76 | KCNMA1 (0.36) | DPP4KCNMA1 | |
| SCHEMBL7961349 | 0.76 | KCNMA1 (0.34) | KDM4EDPP4KCNMA1 | |
| SCHEMBL7964348 | 0.75 | KDM4E (0.35) | KDM4ERECQLDPP4ELANEKCNMA1 | |
| SCHEMBL7965321 | 0.74 | KCNMA1 (0.34) | KDM4EDPP4KCNMA1 | |
| SCHEMBL8329371 | 0.74 | DPP4 (0.35) | KDM4ERECQLDPP4ELANEKCNMA1 | |
| SCHEMBL8324285 | 0.74 | CYP11B2 (0.38) | CNR2CNR1KDM4ERECQLCYP11B2 | |
| SCHEMBL7952967 | 0.73 | DPP4 (0.35) | KDM4ERECQLDPP4ELANEKCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946555-A1 | PYRROLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 1999-10-06 | — | — | EP | claimed |
| WO-1998025925-A1 | PYRROLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1998-06-18 | — | — | WO | claimed |