Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330253 | 0.82 | CYP19A1 (0.52) | CYP19A1ENPP2GRM5KDM4EALDH1A1 | |
| SCHEMBL8329139 | 0.80 | KCNJ1 (0.49) | KCNJ1KCNH2CYP19A1 | |
| SCHEMBL1420076 | 0.72 | KCNJ1 (0.53) | KCNJ1KCNH2ENPP2KDM4EALDH1A1 | |
| SCHEMBL8324537 | 0.71 | KIF11 (0.53) | CYP19A1 | |
| SCHEMBL8328528 | 0.69 | MEN1 (0.49) | KCNJ1KCNH2CYP19A1MEN1ALDH1A1 | |
| SCHEMBL995812 | 0.68 | CA2 (0.50) | ENPP2KDM4EALDH1A1GAA | |
| SCHEMBL8328181 | 0.68 | CYP19A1 (0.38) | CYP19A1GRM5KDM4E | |
| SCHEMBL8443718 | 0.65 | KCNJ1 (0.47) | KCNJ1KCNH2CYP19A1 | |
| SCHEMBL8328066 | 0.65 | CYP19A1 (0.44) | CYP19A1KDM4EALDH1A1HPGD | |
| SCHEMBL8446478 | 0.64 | CYP19A1 (0.64) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640595-B1 | SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-5538976-A | ANTICARCINOGENIC AGENTS AND ENZYME INHIBITORS FOR AROMATASE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0640595-A1 | NOVEL SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |