Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324537 | 0.87 | KIF11 (0.53) | CYP19A1CYP3A4 | |
| SCHEMBL8328528 | 0.84 | MEN1 (0.49) | CYP19A1ALDH1A1TSHRCYP3A4CYP2C19 | |
| SCHEMBL995812 | 0.82 | CA2 (0.50) | CYP2A6ENPP2ALDH1A1CA12CA2 | |
| SCHEMBL8329925 | 0.82 | KCNJ1 (0.41) | CYP19A1ENPP2GRM5ALDH1A1KDM4E | |
| SCHEMBL8328181 | 0.79 | CYP19A1 (0.38) | CYP19A1CYP11B2GRM5CYP11B1CYP3A4 | |
| SCHEMBL25543233 | 0.76 | MMP3 (0.56) | CYP11B2CYP2A6ENPP2ALDH1A1CA12 | |
| SCHEMBL25544161 | 0.76 | MMP3 (0.56) | CYP11B2CYP2A6ENPP2ALDH1A1CA12 | |
| SCHEMBL8328066 | 0.75 | CYP19A1 (0.44) | CYP19A1CYP11B2CYP2A6ALDH1A1CYP11B1 | |
| SCHEMBL25543818 | 0.74 | CYP11B2 (0.50) | CYP11B2CA12CA2CA9CYP11B1 | |
| SCHEMBL25543310 | 0.74 | CYP11B2 (0.50) | CYP11B2CA12CA2CA9CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640595-B1 | SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-5538976-A | ANTICARCINOGENIC AGENTS AND ENZYME INHIBITORS FOR AROMATASE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0640595-A1 | NOVEL SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |