Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.48 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330253 | 0.87 | CYP19A1 (0.52) | CYP3A4CYP19A1 | |
| SCHEMBL524351 | 0.76 | KIF11 (0.86) | KIF11CYP3A4CYP3A5CYP19A1MAOB | |
| SCHEMBL2632415 | 0.75 | KIF11 (0.49) | KIF11CYP3A4CYP3A5CYP19A1MAOB | |
| Hydrochloric Acid SCHEMBL27812058 | 0.74 | KIF11 (0.83) | KIF11CYP3A4CYP3A5CYP19A1MAOB | |
| SCHEMBL2351716 | 0.74 | CYP19A1 (0.59) | KIF11CYP3A4CYP3A5CYP19A1 | |
| SCHEMBL8328528 | 0.74 | MEN1 (0.49) | CYP3A4CYP19A1 | |
| SCHEMBL995812 | 0.72 | CA2 (0.50) | KIF11MAOB | |
| SCHEMBL4298574 | 0.72 | MGLL (0.50) | KIF11 | |
| SCHEMBL8329925 | 0.71 | KCNJ1 (0.41) | CYP19A1 | |
| SCHEMBL8328181 | 0.71 | CYP19A1 (0.38) | CYP3A4CYP19A1VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640595-B1 | SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-5538976-A | ANTICARCINOGENIC AGENTS AND ENZYME INHIBITORS FOR AROMATASE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0640595-A1 | NOVEL SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |