Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330253 | 0.79 | CYP19A1 (0.52) | CYP19A1GRM5CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL8326800 | 0.73 | CYP19A1 (0.44) | CYP19A1GRM5VNN1 | |
| SCHEMBL8324537 | 0.71 | KIF11 (0.53) | CYP19A1CYP3A4VNN1 | |
| SCHEMBL8324262 | 0.69 | CYP19A1 (0.40) | CYP19A1GRM5CYP3A4VNN1 | |
| SCHEMBL8323103 | 0.69 | ESR1 (0.49) | CYP19A1VNN1CYP11B1CYP11B2 | |
| SCHEMBL8327043 | 0.68 | CYP19A1 (0.45) | CYP19A1CYP3A4VNN1 | |
| SCHEMBL27287580 | 0.68 | CYP11B1 (0.44) | CYP19A1GRM5CYP11B1CYP11B2 | |
| SCHEMBL8329925 | 0.68 | KCNJ1 (0.41) | CYP19A1GRM5KDM4E | |
| SCHEMBL6063814 | 0.68 | CYP19A1 (0.38) | CYP19A1GRM5VNN1CYP11B1CYP11B2 | |
| SCHEMBL8328528 | 0.67 | MEN1 (0.49) | CYP19A1CYP3A4PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640595-B1 | SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-5538976-A | ANTICARCINOGENIC AGENTS AND ENZYME INHIBITORS FOR AROMATASE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0640595-A1 | NOVEL SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |