Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.45 |
| ▸ | TUBB | P07437 | 2/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330509 | 0.94 | TNKS2 (0.42) | TNKS2KMT2AALDH1A1TUBB4ATUBB | |
| SCHEMBL8332678 | 0.92 | ALDH1A1 (0.47) | KMT2AALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL8332681 | 0.85 | KMT2A (0.44) | KMT2AALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL8330517 | 0.81 | ALDH1A1 (0.48) | KMT2AALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL8330920 | 0.76 | LMNA (0.53) | KDM4EMAPT | |
| SCHEMBL6774946 | 0.74 | LPAR1 (0.49) | KMT2AALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL491077 | 0.74 | ALDH1A1 (0.62) | KMT2AALDH1A1KDM4EMEN1GAA | |
| SCHEMBL490351 | 0.74 | KMT2A (0.51) | KMT2AALDH1A1KDM4EMEN1GAA | |
| SCHEMBL8233587 | 0.73 | TUBB4A (0.57) | TNKS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7424861 | 0.72 | HTR2A (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |