Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778466 | 0.85 | MEN1 (0.53) | KMT2AALOX5LMNASMN1; SMN2TDP1 | |
| SCHEMBL8330517 | 0.82 | ALDH1A1 (0.48) | KMT2AALDH1A1L3MBTL1TDP1TUBB4A | |
| SCHEMBL6779971 | 0.81 | LMNA (0.56) | LMNASMN1; SMN2 | |
| SCHEMBL6781356 | 0.80 | LMNA (0.53) | KMT2AALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL1856039 | 0.80 | L3MBTL1 (0.50) | KMT2AALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL10816013 | 0.79 | SMN1; SMN2 (0.51) | KMT2AALOX5SMN1; SMN2MAPK1 | |
| SCHEMBL10816014 | 0.79 | SMN1; SMN2 (0.51) | KMT2AALOX5SMN1; SMN2MAPK1 | |
| SCHEMBL7896500 | 0.78 | TUBB4A (0.61) | G6PDTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6783901 | 0.78 | G6PD (0.51) | KMT2AG6PDALDH1A1ALOX5LMNA | |
| SCHEMBL1857414 | 0.78 | SMN1; SMN2 (0.48) | LPAR1KMT2AALOX5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6818643-B1 | 3,9-DIAZABICYCLO(3.3.1)NONAN-2-ONE DERIVATIVES; PEPTIDYL-PROLYL ISOMERASE (PPIASE OR ROTAMASE) INHIBITORS; NEUROPROTECTIVE AGENTS | BRISTOL-MYERS SQUIBB COMPANY | 2004-11-16 | — | — | US | disclosed |
| WO-2001042245-A1 | NEUROTROPHIC BICYCLIC DIAMIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-06-14 | — | — | WO | disclosed |