Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930359 | 0.81 | MAOA (0.43) | POLBALDH1A1MAPTKDM4EMAPK1 | |
| SCHEMBL7027183 | 0.81 | POLB (0.51) | POLBALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL8581655 | 0.81 | PDE10A (0.41) | POLBALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL8740694 | 0.81 | MAPT (0.41) | POLBALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL7756511 | 0.78 | KDM4E (0.48) | POLBALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL8330737 | 0.76 | MEN1 (0.40) | POLBALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL7030411 | 0.75 | SCN9A (0.43) | ALDH1A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL7024083 | 0.75 | POLB (0.43) | POLBALDH1A1MAPTKDM4EMAPK1 | |
| SCHEMBL7756508 | 0.74 | KMT2A (0.46) | POLBALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL7755157 | 0.72 | MAPK14 (0.33) | POLBALDH1A1MAPTRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819119-A4 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN INC (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0819119-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN, INC. (US) | 1998-01-21 | — | — | EP | disclosed |
| WO-1997026245-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN, INC. (US) | 1997-07-24 | — | — | WO | disclosed |