Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 2/20 | 0.32 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965681 | 0.92 | FPR1 (0.33) | DHODHFPR1FPR2BACE1PER2 | |
| SCHEMBL7961641 | 0.91 | BACE1 (0.34) | DHODHFPR1FPR2BACE1PER2 | |
| SCHEMBL7961758 | 0.91 | FPR1 (0.35) | FPR1FPR2BACE1HCRTR1PDE4B | |
| SCHEMBL8326401 | 0.90 | DHODH (0.37) | DHODHPER2HCRTR1KMT2A | |
| SCHEMBL8330821 | 0.86 | DHODH (0.36) | DHODHFPR1FPR2NAPRTFFAR4 | |
| SCHEMBL7965050 | 0.82 | CYP2C19 (0.33) | DHODHPER2HCRTR1PDE4B | |
| SCHEMBL7964338 | 0.81 | CYP11B2 (0.35) | BACE1 | |
| SCHEMBL7961198 | 0.81 | MEN1 (0.34) | PDE4BKMT2A | |
| SCHEMBL7962835 | 0.81 | ALDH1A1 (0.33) | DHODHPER2HCRTR1SCN9A | |
| SCHEMBL7964731 | 0.80 | FPR1 (0.35) | FPR1FPR2PDE4BPDE4DABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946555-A1 | PYRROLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 1999-10-06 | — | — | EP | claimed |
| WO-1998025925-A1 | PYRROLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1998-06-18 | — | — | WO | claimed |