Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8331567 | 0.96 | MAP3K14 (0.30) | MAP3K14 | |
| SCHEMBL8333554 | 0.83 | RARA (0.41) | MAP3K14 | |
| SCHEMBL8332049 | 0.81 | RARA (0.41) | MAP3K14 | |
| SCHEMBL7571998 | 0.74 | — | — | |
| SCHEMBL4373634 | 0.71 | LMNA (0.42) | — | |
| SCHEMBL9054289 | 0.71 | MAPT (0.41) | — | |
| SCHEMBL9053853 | 0.70 | ALDH1A1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL21750681 | 0.70 | MAPT (0.44) | — | |
| SCHEMBL8331366 | 0.68 | RXRA (0.40) | — | |
| SCHEMBL8197285 | 0.68 | AKR1B1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5917082-A | 2,4-pentadienoic acid derivatives having retinoid-like biological activity | ALLERGAN SALES, INC. (US) | 1999-06-29 | — | — | US | disclosed |
| US-5817836-A | 2,4-pentadienoic acid derivatives having retinoid-like biological activity | ALLERGAN (US) | 1998-10-06 | — | — | US | disclosed |
| US-5780647-A | 2,4-Pentadienoic acid derivatives having retinoid-like biological activity | ALLERGAN (US) | 1998-07-14 | — | — | US | disclosed |
| US-5675033-A | FOR TREATMENT OF SKIN DISORDERS | ALLERGAN (US) | 1997-10-07 | — | — | US | disclosed |