Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8333201 | 0.81 | POLB (0.52) | MAPTKDM4EPOLBNPC1ALOX15 | |
| SCHEMBL6930359 | 0.78 | MAOA (0.43) | MAPTKDM4EPOLBGLANPC1 | |
| SCHEMBL8581655 | 0.77 | PDE10A (0.41) | MAPTNPSR1POLBNPC1ALDH1A1 | |
| SCHEMBL7756511 | 0.75 | KDM4E (0.48) | MAPTNPSR1KDM4EPOLBGLA | |
| SCHEMBL8049966 | 0.74 | MAPT (0.46) | MAPTNPSR1KDM4EPOLBGLA | |
| SCHEMBL7027183 | 0.72 | POLB (0.51) | MAPTNPSR1TNKS2KDM4EPOLB | |
| SCHEMBL7024083 | 0.72 | POLB (0.43) | MAPTNPSR1KDM4EPOLBGLA | |
| SCHEMBL7030411 | 0.72 | SCN9A (0.43) | MAPTKDM4EGLAALDH1A1HPGD | |
| SCHEMBL27810295 | 0.71 | L3MBTL1 (0.47) | MAPTNPSR1KDM4EGAAALDH1A1 | |
| SCHEMBL5553018 | 0.70 | L3MBTL1 (0.43) | MAPTNPSR1KDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755457-A4 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN INC (US) | 1997-07-16 | — | — | EP | disclosed |
| EP-0755457-A1 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028495-A1 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1995-10-26 | — | — | WO | disclosed |