Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334114 | 0.87 | SLC9A1 (0.41) | SLC9A1TSHRMTNR1BMTNR1AKDM1A | |
| SCHEMBL8332882 | 0.77 | HTR2A (0.47) | SLC9A1MTNR1BMTNR1ADRD2 | |
| SCHEMBL8329351 | 0.77 | HTR2A (0.47) | SLC9A1MTNR1BMTNR1ADRD2 | |
| SCHEMBL8096225 | 0.73 | MTNR1B (0.51) | SLC9A1MTNR1BMTNR1A | |
| SCHEMBL8096223 | 0.73 | MTNR1B (0.51) | SLC9A1MTNR1BMTNR1A | |
| SCHEMBL8096228 | 0.73 | MTNR1B (0.51) | SLC9A1MTNR1BMTNR1A | |
| SCHEMBL3288096 | 0.73 | TSHR (0.60) | SLC9A1TSHRMTNR1BKDM1ARCOR1 | |
| SCHEMBL3288083 | 0.73 | TSHR (0.60) | SLC9A1TSHRMTNR1BKDM1ARCOR1 | |
| SCHEMBL3288086 | 0.73 | TSHR (0.60) | SLC9A1TSHRMTNR1BKDM1ARCOR1 | |
| SCHEMBL3287364 | 0.70 | SLC9A1 (0.67) | SLC9A1TSHRKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889031-A | CONTROLLING CIRCADIAN RHYTHMS | BRISTOL-MYERS SQUIBB COMPNAY (US) | 1999-03-30 | — | — | US | disclosed |
| US-5753709-A | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-19 | — | — | US | disclosed |