Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8333365 | 0.87 | SLC9A1 (0.47) | SLC9A1MTNR1BMTNR1ATSHRKDM1A | |
| SCHEMBL8334052 | 0.81 | SLC9A1 (0.43) | SLC9A1MTNR1BMTNR1ACACNA1DTSHR | |
| SCHEMBL8329351 | 0.76 | HTR2A (0.47) | SLC9A1MTNR1BMTNR1A | |
| SCHEMBL8332882 | 0.76 | HTR2A (0.47) | SLC9A1MTNR1BMTNR1A | |
| SCHEMBL8103541 | 0.76 | MTNR1B (0.50) | MTNR1BMTNR1A | |
| SCHEMBL8103536 | 0.76 | MTNR1B (0.50) | MTNR1BMTNR1A | |
| SCHEMBL28746510 | 0.69 | MTNR1A (0.57) | MTNR1BMTNR1A | |
| SCHEMBL8333438 | 0.69 | SLC9A1 (0.39) | SLC9A1MTNR1BMTNR1AKDM1ARCOR1 | |
| SCHEMBL8333441 | 0.69 | SLC9A1 (0.39) | SLC9A1MTNR1BMTNR1AKDM1ARCOR1 | |
| SCHEMBL8330356 | 0.68 | SLC9A1 (0.44) | SLC9A1MTNR1BMTNR1ACACNA1DTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753709-A | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-19 | — | — | US | claimed |
| US-5889031-A | CONTROLLING CIRCADIAN RHYTHMS | BRISTOL-MYERS SQUIBB COMPNAY (US) | 1999-03-30 | — | — | US | disclosed |
| US-5753709-A | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-19 | — | — | US | disclosed |