Styrene

Styrene

SCHEMBL8333795

C=Cc1ccccc1.FC(F)=C(F)c1cccc(F)c1F

nearest known ligand 0.45

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
TSHR P16473 1/20 0.45
CES2 O00748 3/20 0.42
CES1 P23141 3/20 0.42
BCHE P06276 1/20 0.42
NFE2L2 Q16236 3/20 0.37
KAT6A Q92794 1/20 0.35
HPGD P15428 1/20 0.34
ALB P02768 1/20 0.33
KLF5 Q13887 1/20 0.31
NPC1 O15118 3/20 0.31
RAB9A P51151 3/20 0.31
KMT2A Q03164 2/20 0.31
ALOX15 P16050 1/20 0.31
TP53 P04637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL1672616 0.85 NFE2L2 (0.36) ALDH1A1TSHRCES2CES1BCHE
SCHEMBL14763442 0.82 NFE2L2 (0.45) CES2CES1BCHENFE2L2KAT6A
SCHEMBL22540 0.82 CES2 (0.58) ALDH1A1CES2CES1BCHEKAT6A
Styrene SCHEMBL28264428 0.80 ALDH1A1 (0.64) ALDH1A1TSHRCES2CES1BCHE
O-Xylene SCHEMBL28242721 0.78 CES2 (0.48) ALDH1A1TSHRCES2CES1BCHE
SCHEMBL979653 0.77 NFE2L2 (0.41) ALDH1A1CES2CES1BCHENFE2L2
SCHEMBL8470422 0.75 CES2 (0.40) CES2CES1BCHEHPGD
Methacrylic Acid SCHEMBL9728600 0.74 CES2 (0.50) ALDH1A1CES2CES1BCHEKAT6A
Styrene SCHEMBL27525049 0.74 ALDH1A1 (0.74) ALDH1A1TSHRNFE2L2ALOX15TP53
Styrene SCHEMBL5868543 0.74 ALDH1A1 (0.82) ALDH1A1TSHRNFE2L2ALOX15TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999010109-A1 METHOD FOR MAKING POLYMER-COATED PIGMENT PARTICLES USING INITIATOR-TREATED PIGMENTS COPYTELE, INC. (US) 1999-03-04 WO claimed
WO-2024033429-A1 SIDE-CHAIN FUNCTIONALIZED POLYSTYRENES AS MEMBRANE MATERIALS FOR ALKALINE WATER ELECTROLYZERS, FUEL CELLS AND FLOW BATTERIES Forschungszentrum Jülich GmbH (DE) 2024-02-15 WO disclosed
CN-102264863-B Conductive polymer, polymer composition, film and organic photoelectric device including same CHEIL IND INC 2015-07-22 CN disclosed