Methacrylic Acid

Methacrylic Acid

SCHEMBL9728600

C=C(C)C(=O)O.FC(F)=C(F)c1cccc(F)c1F

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.50
CES1 P23141 4/20 0.50
BCHE P06276 1/20 0.50
HPGD P15428 1/20 0.41
ALB P02768 1/20 0.40
KAT6A Q92794 1/20 0.38
PTPN1 P18031 1/20 0.36
ERCC5 P28715 1/20 0.36
FEN1 P39748 1/20 0.36
GAA P10253 1/20 0.35
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 1/20 0.34
ALOX15 P16050 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
BDKRB1 P46663 1/20 0.34
KIF11 P52732 1/20 0.33
ATM Q13315 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28317993 0.85 CES2 (0.45) CES2CES1BCHEHPGDKAT6A
SCHEMBL22540 0.82 CES2 (0.58) CES2CES1BCHEHPGDALB
SCHEMBL10983723 0.79 CES2 (0.52) CES2CES1BCHEHPGDALB
O-Xylene SCHEMBL28242721 0.78 CES2 (0.48) CES2CES1BCHEHPGDALB
Styrene SCHEMBL8333795 0.74 ALDH1A1 (0.45) CES2CES1BCHEHPGDALB
SCHEMBL22796816 0.74 CES2 (0.59) CES2CES1BCHEHPGDALB
SCHEMBL5845101 0.73 CES2 (0.56) CES2CES1BCHEHPGDALB
SCHEMBL14040983 0.73 CES2 (0.56) CES2CES1BCHEHPGDALB
SCHEMBL29772247 0.73 CES2 (0.68) CES2CES1BCHEHPGDALB
SCHEMBL717464 0.73 CES2 (0.68) CES2CES1BCHEHPGDALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110231755-B Photoresist composition, pixel defining layer, preparation method and application thereof 京东方科技集团股份有限公司 2020-06-19 CN disclosed
US-5106930-A Copolymer of polysiloxanylalkyl ester of acrylic acid, fluorinated styrene IOPTEX RESEARCH INC. (US) 1992-04-21 US disclosed