Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | TOP2A | P11388 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8336152 | 0.92 | CNR2 (0.37) | CNR2PKMP2RX5P2RX4P2RX7 | |
| SCHEMBL8336013 | 0.88 | P2RX7 (0.31) | P2RX4P2RX7 | |
| SCHEMBL8333655 | 0.82 | — | — | |
| SCHEMBL8341312 | 0.81 | POLB (0.38) | CNR2PKMP2RX5P2RX4P2RX7 | |
| SCHEMBL8335857 | 0.81 | GAA (0.31) | LMNAKMT2ASMN1; SMN2GAA | |
| SCHEMBL8334835 | 0.81 | GAA (0.31) | KMT2AGAA | |
| SCHEMBL8864424 | 0.80 | CNR2 (0.35) | CNR2PKMP2RX5P2RX4P2RX7 | |
| SCHEMBL8334767 | 0.78 | ALDH1A1 (0.33) | LMNAKMT2ASMN1; SMN2GAA | |
| SCHEMBL8339599 | 0.78 | TSHR (0.36) | KMT2AMEN1POLBGAA | |
| SCHEMBL8333752 | 0.78 | HIF1A (0.34) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977177-A | Substituted benzenesulfonylureas and-thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| US-5880155-A | TREATMENT OF CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |