Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8341309 | 0.92 | ALDH1A1 (0.38) | CNR2MEN1KMT2AMAPTLMNA | |
| SCHEMBL8341128 | 0.89 | CNR2 (0.36) | CNR2MEN1KMT2AMAPTLMNA | |
| SCHEMBL8334265 | 0.74 | CNR2 (0.35) | CNR2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL8341129 | 0.70 | CNR2 (0.35) | CNR2LMNASMN1; SMN2 | |
| SCHEMBL8339579 | 0.64 | LMNA (0.36) | CNR2MEN1KMT2AMAPTLMNA | |
| SCHEMBL26942964 | 0.62 | CNR2 (0.54) | CNR2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL8352827 | 0.60 | SMN1; SMN2 (0.60) | CNR2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL8335612 | 0.59 | LMNA (0.40) | CNR2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL19091716 | 0.59 | ALDH1A1 (0.57) | KDM4EMAPTLMNANPC1HPGD | |
| SCHEMBL1578597 | 0.58 | CNR2 (0.61) | CNR2MEN1KMT2ANPC1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977177-A | Substituted benzenesulfonylureas and-thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| US-5880155-A | TREATMENT OF CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |