Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335086 | 0.94 | CNR2 (0.36) | CNR2BCL2BCL2L1MCL1BAD | |
| SCHEMBL8340536 | 0.93 | CNR2 (0.36) | CNR2BCL2BCL2L1MCL1BAD | |
| SCHEMBL8338716 | 0.91 | HTR1A (0.40) | CNR2MCL1MAPTMEN1KMT2A | |
| SCHEMBL8334436 | 0.86 | MCL1 (0.39) | CNR2BCL2BCL2L1MCL1BAD | |
| SCHEMBL8339938 | 0.86 | PRKCZ (0.40) | CNR2BCL2BCL2L1MCL1BAD | |
| SCHEMBL8339556 | 0.85 | MAPT (0.38) | CNR2BCL2BCL2L1MCL1BAD | |
| SCHEMBL8336646 | 0.85 | CNR2 (0.35) | CNR2BCL2BCL2L1MCL1BAD | |
| SCHEMBL8339168 | 0.85 | MCL1 (0.38) | CNR2BCL2BCL2L1MCL1BAD | |
| SCHEMBL8339230 | 0.84 | TUBB4A (0.40) | CNR2MCL1ALDH1A1MAPTMEN1 | |
| SCHEMBL8340220 | 0.83 | PRKCZ (0.41) | MAPTMEN1KMT2ANPSR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948796-A | OSTEOPOROSIS, CANCER, CARDIOVASCULAR DISORDERS | ELI LILLY AND COMPANY (US) | 1999-09-07 | — | — | US | disclosed |