Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8236816 | 0.84 | KMT2A (0.40) | KMT2AMEN1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL8325510 | 0.82 | TUBB4A (0.35) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8324933 | 0.81 | PAX8 (0.36) | L3MBTL1KDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL852663 | 0.76 | KMT2A (0.42) | KMT2AMEN1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL19820663 | 0.71 | MEN1 (0.68) | KMT2AMEN1SMN1; SMN2TP53MAPT | |
| SCHEMBL4070313 | 0.70 | ALDH1A1 (0.40) | KDM4EMAPTALDH1A1LMNAHSD17B10 | |
| SCHEMBL7041342 | 0.68 | L3MBTL1 (0.41) | KMT2AMEN1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL6368471 | 0.65 | BRD4 (0.44) | L3MBTL1SMN1; SMN2PKMMAPTNPC1 | |
| SCHEMBL8226698 | 0.65 | MTNR1A (0.35) | KMT2AMEN1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL31576701 | 0.65 | SMN1; SMN2 (0.34) | KMT2AMEN1SMN1; SMN2TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058254-A1 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |