SCHEMBL8336607

SCHEMBL8336607

CCC(C)(C)c1cc(N)cc(C(C)(C)CC)c1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.38
CA1 P00915 2/20 0.38
LMNA P02545 3/20 0.38
RECQL P46063 1/20 0.38
ALDH1A1 P00352 4/20 0.37
TSHR P16473 3/20 0.37
MEN1 O00255 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP3A4 P08684 2/20 0.37
MAPK1 P28482 2/20 0.37
BLM P54132 2/20 0.37
KMT2A Q03164 2/20 0.37
ATM Q13315 2/20 0.37
HIF1A Q16665 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
ALOX15 P16050 2/20 0.37
GMNN O75496 1/20 0.37
GABBR2 O75899 1/20 0.37
TP53 P04637 1/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8339389 0.94 CA2 (0.48) CA2CA1LMNARECQLALDH1A1
SCHEMBL8341121 0.91 LMNA (0.33) CA2CA1LMNARECQLALDH1A1
SCHEMBL8333168 0.88 ESR1 (0.42) CA2CA1LMNARECQLALDH1A1
SCHEMBL9546317 0.85 ALDH1A1 (0.50) CA2CA1LMNARECQLALDH1A1
SCHEMBL8335913 0.83 LMNA (0.36) CA2CA1LMNARECQLALDH1A1
SCHEMBL9188294 0.82 CA2 (0.41) CA2CA1LMNARECQLALDH1A1
SCHEMBL11587517 0.82 ALDH1A1 (0.46) CA2CA1LMNAALDH1A1TSHR
SCHEMBL8340901 0.81 SHBG (0.41) CA2CA1LMNARECQLALDH1A1
SCHEMBL8336744 0.80 CNR2 (0.42) CA2CA1LMNARECQLALDH1A1
SCHEMBL1160345 0.80 SMN1; SMN2 (0.41) CA2CA1LMNARECQLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5981065-A ELECTRICAL CONDUCTORS HAVING GREASE FILLED INTERSTICES THEREBETWEEN, EACH ELECTRICAL CONDUCTOR COVERING WITH POLYOLEFINS LAYER AND THE REACTION PRODUCT OF A HINDERED AMINE AMIC ACID HYDRAZIDE, A PHENOL OR AN AMINE HYDRAZIDE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-11-09 US disclosed
EP-0459950-B1 Stabilisation of dyes on polyamide fibres CIBA GEIGY AG (CH) 1997-03-12 EP disclosed
EP-0438381-B1 Stabilization of dyes on polyamide fibres CIBA GEIGY AG (CH) 1995-04-05 EP disclosed
US-5356443-A Treating fiber before fixation step with sterically hindered phenol and sulfo containing compound CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
WO-1993024935-A1 TELEPHONE CABLES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-12-09 WO disclosed
EP-0303280-B1 PHENOLIC ANTIOXIDANT HYDRAZIDES ATOCHEM NORTH AMERICA, INC. (US) 1993-03-24 EP disclosed
US-5181935-A THERMAL AND PHOTOCHEMICAL STABILIZATION OF DYEINGS ON POLYAMIDE FIBERS:STERICALLY HINDERED PHENOL AND ULTRA-VIOLET ABSORBER CIBA-GEIGY CORPORATION (US) 1993-01-26 US disclosed
EP-0303986-B1 MULTIPURPOSE POLYMER BOUND STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-07-29 EP disclosed
US-5096974-A Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-5096456-A Exhaust or continuous dyeing; carpets automotive fabrics, brassiers CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
EP-0459950-A1 Stabilisation of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-12-04 EP disclosed
EP-0438381-A1 Stabilization of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed
EP-0303280-A2 Phenolic antioxidant hydrazides ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed
US-4801749-A Phenolic antioxidant hydrazides PENNWALT CORPORATION (US) 1989-01-31 US disclosed