Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8336011 | 0.83 | LMNA (0.33) | — | |
| SCHEMBL8333652 | 0.77 | — | — | |
| SCHEMBL8864419 | 0.77 | SIGMAR1 (0.38) | SIGMAR1 | |
| SCHEMBL8865198 | 0.69 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL8335851 | 0.66 | CNR2 (0.38) | CNR2 | |
| SCHEMBL8334765 | 0.65 | HPGD (0.37) | CNR2 | |
| SCHEMBL8334832 | 0.65 | CNR2 (0.37) | CNR2 | |
| SCHEMBL8339597 | 0.64 | KMT2A (0.37) | — | |
| SCHEMBL8334475 | 0.64 | CNR1 (0.33) | CNR2 | |
| SCHEMBL8338167 | 0.58 | HPGD (0.39) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977177-A | Substituted benzenesulfonylureas and-thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| US-5880155-A | TREATMENT OF CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |