Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | YAP1 | P46937 | 2/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335851 | 0.81 | CNR2 (0.38) | KMT2AMEN1 | |
| SCHEMBL8334765 | 0.79 | HPGD (0.37) | KMT2AMEN1MAPT | |
| SCHEMBL8334832 | 0.79 | CNR2 (0.37) | KMT2AMEN1RAB9AMAPT | |
| SCHEMBL8391019 | 0.76 | EPHX2 (0.51) | KMT2AYAP1TEAD4NPC1RAB9A | |
| SCHEMBL8340993 | 0.74 | EPHX2 (0.36) | KMT2AMEN1EPHX2 | |
| SCHEMBL8336540 | 0.74 | CNR2 (0.40) | KMT2A | |
| SCHEMBL8338167 | 0.73 | HPGD (0.39) | MAPT | |
| SCHEMBL8341066 | 0.72 | — | — | |
| SCHEMBL8336209 | 0.71 | GPR88 (0.35) | KMT2AMEN1 | |
| SCHEMBL8334475 | 0.70 | CNR1 (0.33) | KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8245556-A | — | — | None | — | — | JP | disclosed |
| US-5977177-A | Substituted benzenesulfonylureas and-thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| US-5880155-A | TREATMENT OF CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |
| JP-H08245556-A | SUBSTITUTED BENZENESULFONYLUREA AND-THIOUREA, THEIR PREPARATION AND THEIR USE FOR PHARMACEUTICAL PREPARATION BASED ON THE COMPOUNDS, AND MBDICAMENT CONTAINING THEM | HOECHST AG | 1996-09-24 | — | — | JP | disclosed |