Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702592 | 0.85 | LDHA (0.46) | ALOX5CALM1MMP1F2RL1ALDH1A1 | |
| SCHEMBL2722383 | 0.76 | F2RL1 (0.60) | ALOX5F2RL1ALDH1A1POLB | |
| SCHEMBL27459521 | 0.76 | ALDH1A1 (0.47) | ANPEPERAP2F2RL1ALDH1A1 | |
| SCHEMBL6934308 | 0.75 | CYP1A2 (0.49) | MMP1ALDH1A1 | |
| SCHEMBL5495307 | 0.75 | S1PR1 (0.51) | S1PR2S1PR1 | |
| SCHEMBL5495309 | 0.75 | S1PR1 (0.51) | S1PR2S1PR1 | |
| Trifluoroacetic Acid SCHEMBL4313504 | 0.74 | ALOX15 (0.47) | ALOX5CALM1 | |
| SCHEMBL1586966 | 0.74 | TAAR1 (0.56) | ALOX5CALM1 | |
| SCHEMBL1134589 | 0.74 | PPARG (0.47) | ALOX5CALM1MMP1ANPEPERAP2 | |
| SCHEMBL1134521 | 0.74 | PPARG (0.52) | MMP1ALDH1A1MMP2MMP3CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056750-A1 | CYCLOPENTIL-SUBSTITUTED GLUTARAMIDE COMPOUNDS AS ENDOPEPTIDASE INHIBITORS | PFIZER LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |