Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9672147 | 0.87 | PTPN1 (0.39) | TSHRHTTTDP1LMNAKDM4E | |
| SCHEMBL9862075 | 0.82 | THRB (0.39) | TSHRTHRBHTTPOLBLMNA | |
| SCHEMBL9674008 | 0.81 | TYMS (0.38) | TSHRHTTPOLBLMNAKDM4E | |
| SCHEMBL9321984 | 0.79 | ALDH1A1 (0.37) | TSHRHTTPOLBLMNAKDM4E | |
| SCHEMBL3157120 | 0.79 | L3MBTL1 (0.42) | TSHRTHRBELANELMNAL3MBTL1 | |
| SCHEMBL10385058 | 0.79 | KDM4E (0.44) | TSHRTHRBELANETDP1KDM4E | |
| SCHEMBL285513 | 0.78 | TSHR (0.38) | TSHRHTTPOLBLMNAKDM4E | |
| SCHEMBL9672140 | 0.78 | TSHR (0.41) | TSHRHTTLMNAKDM4EL3MBTL1 | |
| SCHEMBL9183227 | 0.76 | L3MBTL1 (0.44) | TSHRELANELMNAKDM4EL3MBTL1 | |
| SCHEMBL2153635 | 0.75 | PTPN1 (0.40) | TSHRTHRBELANETDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5959002-A | PROVIDES ONE-PACK TYPE ANCHOR BOLT-FIXING; STORAGE STABILITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1999-09-28 | — | — | US | disclosed |
| US-5908876-A | Optical resin composition comprising a thiourethane prepolymer and use thereof | MITSUI CHEMICALS, INC. (JP) | 1999-06-01 | — | — | US | disclosed |
| EP-0472106-B1 | Pulverulent ink and printing methods | KAO CORP (JP) | 1994-02-16 | — | — | EP | disclosed |
| EP-0472106-A2 | Pulverulent ink and printing methods | KAO CORPORATION (JP) | 1992-02-26 | — | — | EP | disclosed |