Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.47 |
| ▸ | CCR5 | P51681 | 3/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8337276 | 0.85 | PTGER1 (0.49) | MAOBPTGER1MRGPRX4CCR5LRRK2 | |
| SCHEMBL4723723 | 0.82 | LRRK2 (0.58) | CCR5LRRK2PARP1LMNAPOLB | |
| SCHEMBL8337852 | 0.80 | PTGES (0.59) | CCR5LRRK2PARP1 | |
| SCHEMBL8336987 | 0.79 | LRRK2 (0.53) | CCR5LRRK2PARP1LMNAPOLB | |
| SCHEMBL8337376 | 0.79 | MEN1 (0.54) | PTGER1CCR5LRRK2PARP1LMNA | |
| SCHEMBL8243758 | 0.76 | LRRK2 (0.58) | PTPN1PTGER1RXRARXRBRXRG | |
| SCHEMBL5699854 | 0.76 | PTPN1 (0.64) | PTPN1PTGER1RXRARXRBRXRG | |
| SCHEMBL30679655 | 0.76 | PTPN1 (0.64) | PTPN1PTGER1RXRARXRBRXRG | |
| SCHEMBL27522244 | 0.76 | MAOB (0.52) | MAOBPTGER1RXRARXRBRXRG | |
| SCHEMBL856030 | 0.75 | RXRA (0.70) | MAOBPTPN1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014844-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TRANSTECH PHARMA, INC. (US) | 2004-02-19 | — | — | WO | disclosed |