Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 3/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.44 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.43 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8337229 | 0.85 | MAOB (0.53) | PTGER1CCR5PARP1LRRK2LMNA | |
| SCHEMBL6700864 | 0.82 | RXRA (0.51) | PTGER1USP28USP25MRGPRX4MAOB | |
| SCHEMBL8337852 | 0.82 | PTGES (0.59) | CCR5PARP15PARP10PARP1LRRK2 | |
| SCHEMBL8336987 | 0.81 | LRRK2 (0.53) | CCR5PARP15PARP1LRRK2LMNA | |
| SCHEMBL4723723 | 0.80 | LRRK2 (0.58) | CCR5PARP1LRRK2LMNA | |
| SCHEMBL30900302 | 0.80 | DGAT1 (0.50) | PARP1MAOBSLC6A4 | |
| SCHEMBL6700568 | 0.80 | MAOB (0.48) | PTGER1CCR5LRRK2USP28USP25 | |
| SCHEMBL6702523 | 0.78 | PTGER1 (0.47) | PTGER1USP28USP25MRGPRX4MAOB | |
| SCHEMBL2534007 | 0.78 | PTGDR2 (0.49) | PTGER1CCR5USP28USP25LMNA | |
| SCHEMBL30679656 | 0.78 | PTGDR2 (0.49) | PTGER1CCR5USP28USP25LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014844-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TRANSTECH PHARMA, INC. (US) | 2004-02-19 | — | — | WO | disclosed |