Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CCR5 | P51681 | 3/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723723 | 0.81 | LRRK2 (0.58) | CCR5PARP1LRRK2LMNA | |
| SCHEMBL8337852 | 0.79 | PTGES (0.59) | CCR5PARP1LRRK2 | |
| SCHEMBL8337229 | 0.79 | MAOB (0.53) | CCR5PTGER1PARP1LRRK2LMNA | |
| SCHEMBL8336987 | 0.78 | LRRK2 (0.53) | CCR5PARP1LRRK2LMNA | |
| SCHEMBL25227765 | 0.77 | MEN1 (0.51) | MEN1KMT2APARP1LMNAHTT | |
| SCHEMBL8337276 | 0.77 | PTGER1 (0.49) | CCR5PTGER1PARP1LRRK2LMNA | |
| SCHEMBL3364550 | 0.75 | PTGDR2 (0.53) | KMT2ALMNAMAPK1RAB9A | |
| SCHEMBL21569260 | 0.74 | LMNA (0.62) | MEN1KMT2ALMNAHTTMAPK1 | |
| SCHEMBL3885337 | 0.74 | FOLH1 (0.60) | MEN1KMT2APTGER1LRRK2LMNA | |
| SCHEMBL16997481 | 0.73 | HPGD (0.52) | MEN1KMT2ALMNAHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014844-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TRANSTECH PHARMA, INC. (US) | 2004-02-19 | — | — | WO | disclosed |