Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 7/20 | 0.50 |
| ▸ | CTSK | P43235 | 7/20 | 0.49 |
| ▸ | CTSL | P07711 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.39 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4769116 | 0.78 | CPB2 (0.42) | CTSSCTSKCTSL | |
| SCHEMBL4769110 | 0.78 | CPB2 (0.42) | CTSSCTSKCTSL | |
| SCHEMBL5983467 | 0.77 | CTSS (0.53) | ALDH1A1CTSSCTSKCTSLL3MBTL1 | |
| SCHEMBL5983460 | 0.77 | CTSS (0.53) | ALDH1A1CTSSCTSKCTSLL3MBTL1 | |
| SCHEMBL8334687 | 0.76 | CTSS (0.56) | ALDH1A1CTSSCTSKCTSLL3MBTL1 | |
| SCHEMBL6221912 | 0.74 | CTSK (0.62) | CTSSCTSKCTSL | |
| SCHEMBL8335497 | 0.74 | CTSK (0.62) | CTSSCTSKCTSL | |
| SCHEMBL4763256 | 0.73 | ALDH1A1 (0.45) | ALDH1A1CTSLL3MBTL1 | |
| SCHEMBL4763260 | 0.73 | ALDH1A1 (0.45) | ALDH1A1CTSLL3MBTL1 | |
| SCHEMBL5528235 | 0.73 | CTSL (0.71) | ALDH1A1CTSSCTSKCTSLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004017911-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |