Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3231863 | 0.79 | PTGS2 (0.44) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL8053596 | 0.77 | GAA (0.44) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL8336761 | 0.77 | GRM5 (0.39) | MEN1KMT2AABCB11PTGS2 | |
| SCHEMBL8605251 | 0.75 | MAPT (0.48) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL6171737 | 0.73 | ALOX15 (0.48) | ALOX15MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3173817 | 0.69 | PARP1 (0.68) | ALOX15NPC1RAB9AERCC5FEN1 | |
| SCHEMBL6170838 | 0.68 | MEN1 (0.81) | ALOX15MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6172428 | 0.68 | MEN1 (0.62) | ALOX15MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1133114 | 0.68 | ATM (0.71) | ALOX15NPC1RAB9AERCC5FEN1 | |
| SCHEMBL31514279 | 0.68 | ATM (0.71) | ALOX15NPC1RAB9AERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939417-A | 1,3,6-trihydro-6-aza-3-oxapentalen-2-one derivatives for the treatment of neoplasia | CELL PATHWAYS INC (US) | 1999-08-17 | — | — | US | disclosed |