Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8606847 | 0.88 | HDAC6 (0.43) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3231863 | 0.86 | PTGS2 (0.44) | MAPTMEN1KMT2ASRD5A2ALDH1A1 | |
| SCHEMBL8336761 | 0.83 | GRM5 (0.39) | MEN1KMT2ATSHRAKR1C2SRD5A2 | |
| SCHEMBL8053596 | 0.81 | GAA (0.44) | MAPTMEN1KMT2ACYP2C9HDAC6 | |
| SCHEMBL7676938 | 0.77 | MAPT (0.52) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3992020 | 0.77 | ALDH1A1 (0.41) | MAPTCYP1A2CYP3A4CYP2C9AKR1C2 | |
| SCHEMBL7678368 | 0.76 | MAPT (0.51) | MAPTMEN1KMT2AAKR1C2CA1 | |
| SCHEMBL11859212 | 0.76 | HPGD (0.56) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL8338116 | 0.75 | ALOX15 (0.51) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL9724259 | 0.73 | ALDH1A1 (0.43) | MAPTMEN1KMT2ASRD5A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721347-A | Esters and amides of substituted pyrrole acetic acids | CELL PATHWAYS, INC. (US) | 1998-02-24 | — | — | US | disclosed |
| EP-0485157-A2 | Esters and amides of substituted pyrrole acetic acids | FGN, INC. (US) | 1992-05-13 | — | — | EP | disclosed |